Calcium Thioglycolate
A white, crystalline powder predominantly used as the active chemical agent in over-the-counter hair removal creams (depilatories)
Calcium Thioglycolate
- CAS Number: 5793-98-6; 814-71-1
- Molecular Formula: C4H6CaO4S
- EINECS No.: 212-402-5
- Purity (%): ≥99%
- Appearance: white powder or crystalline solid
- Packing: 20KG/Drum
- Other Names: Acetic acid, mercapto-, calcium salt (2:1); Calcium 2-sulfanylacetate; Anhydrous calcium thioglycolate
Calcium Thioglycolate Specification
| ITEMS | SPECIFICATIONS |
| Content, % | ≥99% |
| Iron ion content(mg/kg) | <0.3 |
| Hg(mg/kg) | <0.05 |
| As(mg/kg) | <1 |
| Pb(mg/kg) | <5 |
| Cd(mg/kg) | <0.5 |
Differences Between Calcium Thioglycolate Trihydrate and Anhydrous:
Most Common Form: The trihydrate (with three water molecules) is the standard commercial and research form. The anhydrous form (without water) is less common.
Different CAS Numbers: Trihydrate uses CAS 5793-98-6; anhydrous uses CAS 814-71-1.
Appearance Same but Structure Different: Both are white to off-white crystalline powders, but the trihydrate contains water molecules inside its crystal structure.
Heating Changes the Trihydrate: When heated above 95°C, the trihydrate slowly loses its water. At 270-290°C, it melts and decomposes.
Solubility Similar: Both forms are soluble in water, slightly soluble in alcohol and chloroform, but not soluble in ether or benzene.
Application Difference: The trihydrate is widely used in cosmetics (hair waving, depilatory creams) and leather processing because it is more stable and gentler on skin. The anhydrous form is mainly used in strong chemical reduction reactions and research where high purity and no water are required.
Calcium Thioglycolate for Sale
Gentle on Skin: Our Calcium Thioglycolate (trihydrate) is much milder than other thioglycolates, making it ideal for depilatory creams and sensitive skin formulations.
Stable & Easy to Use: The trihydrate form is stable during normal storage and easy to formulate into creams, lotions, or aqueous solutions.
Multi‑Industry Performance: Works effectively as a reducing agent for hair waving, depilatories, leather processing, and chemical synthesis.
What is Calcium Thioglycolate Used for
Depilatory Creams: It is the main active ingredient in hair removal creams. It breaks down keratin proteins in hair, allowing the hair to be wiped away gently without damaging the skin.
Hair Waving & Straightening: It acts as a reducing agent to soften and restructure the disulfide bonds in hair. This gives long‑lasting curls or smooth straight styles, especially in professional hair salons.
Leather Processing: In the leather industry, it is used to remove hair from animal hides efficiently. It also helps improve the softness and flexibility of the final leather product.
Chemical Synthesis: It serves as a mild reducing agent in the production of various organic compounds and metal complexes. It is valuable for research and industrial chemical reactions.
Cosmetic Formulations: It is added to creams and lotions to stabilize the product and provide mild reducing properties. This helps extend shelf life and improves the feel on the skin.
FAQ of Calcium Thioglycolate
The trihydrate form is more stable, easier to handle, and provides a gentler action with reduced irritation compared to the anhydrous form. The stable trihydrate form ensures consistent quality and easy formulation.
We use iodometric titration for assay and chelatometric titration for purity. Certificates of Analysis (CoA) for all batches are provided with each shipment.
When properly formulated in regulated cosmetic products within approved concentration limits, it is considered safe for use. However, it can cause skin irritation in some individuals, especially those with known sensitivity. It is recommended to conduct skin patch tests before full product launch.
20kg/drum
Store at room temperature in a cool, dark place (below 25°C, ideal <15°C). Shelf life is up to 24 months when containers remain sealed. Avoid storing at temperatures above 30°C or below freezing ( +5°C to +30°C is acceptable). If frozen, thaw at room temperature before use — quality is not affected. Keep away from air, strong acids, and incompatible materials.
Calcium Thioglycolate Supplier
HOO CHEMTEC: Your Trusted Source for Calcium Thioglycolate
We are a direct supplier of high-purity Calcium Thioglycolate, the most stable and widely used grade for depilatory creams, hair waving, and leather processing. Our product is a white to off-white crystalline powder with purity ≥99%, specifically chosen for its mildness and stability in sensitive formulations.
Why choose us?
Consistent quality – every batch is tested in our ISO‑certified lab for purity, heavy metals, and pH. Certificate of Analysis (CoA) provided with each shipment, ensuring full traceability.
Stable supply – backed by strong manufacturing partnerships and reliable inventory, we guarantee on‑time delivery even for large or repeat orders.
Expert support – our technical team understands cosmetic and leather applications. We help you select the right grade and provide formulation advice for creams, lotions, or aqueous solutions.
Flexible packaging – from 1kg lab samples for testing to 20kg drums or bulk industrial packaging. Custom options available upon request.
Free samples – available for pre‑order testing. Contact us with your application, and we will send the appropriate sample for evaluation.
Partner with HOO CHEMTEC for dependable Calcium Thioglycolate Trihydrate and professional, responsive service. Contact us today to request a free sample or quote.
